Human Reproduction Update, Vol.5, No.6 pp.565-620, 1999
© European Society of Human Reproduction and Embryology 1999; all rights reserved
The recent saga of cardiovascular disease and safety of oral contraceptives
0 Editorial office, ESHRE Journals, Moor Barns Farmhouse, Madingley Road, Coton, Cambridge CB3 7PG, UK 1 Clinique Marignan, 8 Rue Marignan, Paris, France z Corresponding author
Abstract
This review presents detailed risk estimates from relevant epidemiological and other studies on the comparative safety of second and third generation oral contraceptives (OC). Written with the intention of presenting a repository of the available information, it also discourses briefly into the symptomatology and diagnosis of diseases associated with OC use and presents some of the critical comments made about various epidemiological analyses. A general critique including observations and opinions of various investigators completes the review. We stress that our own opinions on the various studies, or an attempt to adjudge the relative safety of second and third generation OC, are not given since they form the substance of our second paper which completes this symposium.
Key words: cardiovascular disease/epidemiology/oral contraception/pill scare/safety
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