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Human Reproduction Update, Vol.9, No.2 pp.131-138, 2003
© European Society of Human Reproduction and Embryology 2003; all rights reserved

Endometrial wave-like activity in the non-pregnant uterus

I. van Gestel1, M. M. IJland1, H. J. Hoogland1 and J. L. H. Evers1

1 Department of Obstetrics and Gynecology, Research Institute GROW, University Hospital of Maastricht, Maastricht, the Netherlands

To whom correspondence should be addressed at: I. van Gestel , P. Debeyelaan 25, P.O. Box 5800, 6202 AZ Maastricht, the Netherlands. E-mail: ivge{at}sgyn.azm.nl

Abstract

The non-pregnant uterus shows wave-like activity throughout the menstrual cycle. This uterine activity was first detected using intra-uterine pressure recordings. The use of ultrasound has made it possible to study the movements of the uterus in a non-invasive manner. Throughout the menstrual cycle, several wavelike activity patterns have been described; these patterns change throughout the menstrual cycle and are governed by steroid hormones. An adequate wave pattern seems to be related to successful reproduction in spontaneous cycles and assisted reproduction. Further insight into the phenomenon of endometrial wave-like activity might offer an opportunity to correct abnormal wave patterns and thereby improve pregnancy rates.

Key words: endometrial waves / endometrial wave classification system / non-pregnant uterus / transvaginal ultrasound / uterine contractions


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