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Human Reproduction Update, Vol.2, No.6 pp.531-539, 1996
© European Society of Human Reproduction and Embryology 1996; all rights reserved

Cystic fibrosis, Duchenne muscular dystrophy and preimplantation genetic disorders

J Liu0,z, W Lissens1, P Devroey0, I Liebaers1 and A van Steirteghem0

0 Centre for Reproductive Medicine and 1 Department of Medical Genetics, University Hospital, Dutch-speaking Brussels Free University, Laarbeeklaan 101, B-1090 Brussels, Belgium z Corresponding author at: The GBMC Fertility Center, The Greater Baltimore Medical Center, 6569 North Charles Street, Suite 406, Baltimore, MD 21204, USA

Abstract

Cystic fibrosis (CF) is the most common genetic disease among Caucasians. Duchenne muscular dystrophy (DMD) is one of the most common X-linked genetic disorders. The CF and DMD genes were discovered a few years ago, which provided the possibility for prenatal diagnosis and preimplantation diagnosis of CF and DMD by using specific DNA analysis. In this article, CF, DMD, the process of the identification of the genes of CF and DMD and preimplantation genetic diagnosis are briefly described.

Keywords: cystic fibrosis/Duchenne muscular dystrophy/preimplantation diagnosis


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