| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Human Reproduction Update, Vol.4, No.4 pp.323-336, 1998
© European Society of Human Reproduction and Embryology 1998; all rights reserved
Surgical and medical treatment of adenomyosis
Department of Obstetrics and Gynaecology, Monash University, Melbourne, Australia
Abstract
The treatment of adenomyosis has been limited by the difficulty and delay associated with the diagnosis, often not until after hysterectomy. Magnetic resonance imaging, high resolution vaginal ultrasound and uterine biopsy have improved early detection of adenomyosis. Drug therapy may be effective in controlling symptoms but the frequent coexistence of endometriosis and the lack of controlled studies make their efficacy difficult to quantify. Conservative surgery involving endomyometrial ablation, laparoscopic myometrial electrocoagulation or excision has proven to be effective in >50% of patients, although follow-up has been restricted to 3 years. Hysterectomy will still be necessary in severe cases of adenomyosis. Early diagnosis may improve treatment. Investigations are indicated in women with menstrual pain or menorrhagia not responding to drug therapy.
Key words: adenomyosis/conservative surgery/drug treatment
![]()
CiteULike
Connotea
Del.icio.us What's this?
This article has been cited by other articles:
![]() |
C. C Dim, P. U Agu, N. R Dim, and A. C Ikeme Adenomyosis and uterine rupture during labour in a primigravida: an unusual obstetric emergency in Nigeria Trop Doct, October 1, 2009; 39(4): 250 - 251. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. K Mehasseb and M. A Habiba Adenomyosis uteri: an update Obstet Gynaecol (Lond), January 1, 2009; 11(1): 41 - 47. [Abstract] [Full Text] [PDF] |
||||
![]() |
X. Zhang, H. Yuan, L. Deng, F. Hu, J. Ma, and J. Lin Evaluation of the efficacy of a danazol-loaded intrauterine contraceptive device on adenomyosis in an ICR mouse model Hum. Reprod., September 1, 2008; 23(9): 2024 - 2030. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. A. Hobson, M. Z. Kiss, T. Varghese, A. M. Sommer, M. A. Kliewer, J. A. Zagzebski, T. J. Hall, J. Harter, E. M. Hartenbach, and E. L. Madsen In Vitro Uterine Strain Imaging: Preliminary Results J. Ultrasound Med., July 1, 2007; 26(7): 899 - 908. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. D. Kim, S. Kim, N. K. Kim, M. H. Lee, E. H. Ahn, H. J. Kim, J. H. Cho, and S. H. Cha Long-Term Results of Uterine Artery Embolization for Symptomatic Adenomyosis Am. J. Roentgenol., January 1, 2007; 188(1): 176 - 181. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. Hever, R.B. Roth, P.A. Hevezi, J. Lee, D. Willhite, E.C. White, E.M. Marin, R. Herrera, H.M. Acosta, A.J. Acosta, et al. Molecular characterization of human adenomyosis Mol. Hum. Reprod., December 1, 2006; 12(12): 737 - 748. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. Chopra, A. S. Lev-Toaff, F. Ors, and D. Bergin Adenomyosis:common and uncommon manifestations on sonography and magnetic resonance imaging. J. Ultrasound Med., May 1, 2006; 25(5): 617 - 627. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. Rabinovici, Y. Inbar, S.C. Eylon, E. Schiff, A. Hananel, and D. Freundlich Pregnancy and live birth after focused ultrasound surgery for symptomatic focal adenomyosis: a case report Hum. Reprod., May 1, 2006; 21(5): 1255 - 1259. [Abstract] [Full Text] [PDF] |
||||
![]() |
J.-P. Pelage, D. Jacob, A. Fazel, J. Namur, A. Laurent, R. Rymer, and O. Le Dref Midterm Results of Uterine Artery Embolization for Symptomatic Adenomyosis: Initial Experience Radiology, March 1, 2005; 234(3): 948 - 953. [Abstract] [Full Text] [PDF] |
||||
![]() |
B. McLucas, R. Perrella, L. Adler, G. P. Siskin, M. E. Tublin, K. Dowling, and E. G. Dolen Embolization for the Treatment of Adenomyosis Am. J. Roentgenol., April 1, 2002; 178(4): 1028 - 1029. [Full Text] [PDF] |
||||
![]() |
M. Bazot, A. Cortez, E. Darai, J. Rouger, J. Chopier, J.-M. Antoine, and S. Uzan Ultrasonography compared with magnetic resonance imaging for the diagnosis of adenomyosis: correlation with histopathology Hum. Reprod., November 1, 2001; 16(11): 2427 - 2433. [Abstract] [Full Text] [PDF] |
||||
![]() |
G. Leyendecker Redefining endometriosis: Endometriosis is an entity with extreme pleiomorphism Hum. Reprod., January 1, 2000; 15(1): 4 - 7. [Full Text] [PDF] |
||||






