Skip Navigation



Human Reproduction Update Advance Access published online on September 2, 2005
Human Reproduction Update, doi:10.1093/humupd/dmi033
This Article
Right arrow FREE Full Text (PDF) Freely available
Right arrow All Versions of this Article:
12/1/65    most recent
dmi033v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Pangas, S. A.
Right arrow Articles by Rajkovic, A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Pangas, S. A.
Right arrow Articles by Rajkovic, A.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The Author 2005. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions@oupjournals.org
Received May 3, 2005
Accepted June 27, 2005

Article

Transcriptional regulation of early oogenesis: in search of masters

Stephanie A. Pangas 1 and Aleksandar Rajkovic 2*

1 Department of Pathology, Baylor College of Medicine, Houston, TX, USA
2 Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, TX, USA

* To whom correspondence should be addressed.
Aleksandar Rajkovic, E-mail: rajkovic{at}bcm.tmc.edu


  Abstract

Transcription factors in the germline play important roles in ovary formation and folliculogenesis, and control both oocyte development and somatic cell function. Factor in the germline (Figla) and newborn ovary homeobox gene (Nobox) represent a growing number of oocyte-specific transcription factors that regulate genes unique to oocytes. Studies on oocyte-specific transcription factors are important in understanding the genetic pathways essential for oogenesis, pluripotency, and embryonic development. Likely, these genes regulate reproductive life span and represent candidate genes for reproductive disorders, such as premature ovarian failure, and infertility. Therefore, oocytespecific transcription factors, and oocyte-specific genes regulated by such factors, are attractive tissue-specific pharmacological targets to regulate human fertility.

Keywords: folliculogenesis/human fertility/mouse knockout models/oocyte-specific transcription factors/oogenesis.
Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Mol Hum ReprodHome page
K. Duffin, R.A.L. Bayne, A.J. Childs, C. Collins, and R.A. Anderson
The forkhead transcription factor FOXL2 is expressed in somatic cells of the human ovary prior to follicle formation
Mol. Hum. Reprod., December 1, 2009; 15(12): 771 - 777.
[Abstract] [Full Text] [PDF]

Home page
 Biol. Reprod.Home page
J. Tejomurtula, K.-B. Lee, S. K. Tripurani, G. W. Smith, and J. Yao
Role of Importin Alpha8, a New Member of the Importin Alpha Family of Nuclear Transport Proteins, in Early Embryonic Development in Cattle
Biol Reprod, August 1, 2009; 81(2): 333 - 342.
[Abstract] [Full Text] [PDF]

Home page
 Endocr. Rev.Home page
C. R. Nicholas, S. L. Chavez, V. L. Baker, and R. A. Reijo Pera
Instructing an Embryonic Stem Cell-Derived Oocyte Fate: Lessons from Endogenous Oogenesis
Endocr. Rev., May 1, 2009; 30(3): 264 - 283.
[Abstract] [Full Text] [PDF]

Home page
 ReproductionHome page
E. A McLaughlin and S. C McIver
Awakening the oocyte: controlling primordial follicle development
Reproduction, January 1, 2009; 137(1): 1 - 11.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
H.-T. Bui, S. Wakayama, S. Kishigami, J.-H. Kim, N. Van Thuan, and T. Wakayama
The cytoplasm of mouse germinal vesicle stage oocytes can enhance somatic cell nuclear reprogramming
Development, December 1, 2008; 135(23): 3935 - 3945.
[Abstract] [Full Text] [PDF]

Home page
 ReproductionHome page
E. Gazdag, A. Rajkovic, M. E. Torres-Padilla, and L. Tora
Analysis of TATA-binding protein 2 (TBP2) and TBP expression suggests different roles for the two proteins in regulation of gene expression during oogenesis and early mouse development
Reproduction, July 1, 2007; 134(1): 51 - 62.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Endocrinol.Home page
D.-S. Wang, T. Kobayashi, L.-Y. Zhou, B. Paul-Prasanth, S. Ijiri, F. Sakai, K. Okubo, K.-i. Morohashi, and Y. Nagahama
Foxl2 Up-Regulates Aromatase Gene Transcription in a Female-Specific Manner by Binding to the Promoter as Well as Interacting with Ad4 Binding Protein/Steroidogenic Factor 1
Mol. Endocrinol., March 1, 2007; 21(3): 712 - 725.
[Abstract] [Full Text] [PDF]

Home page
 Hum Reprod UpdateHome page
K.R. Barnett, C. Schilling, C.R. Greenfeld, D. Tomic, and J.A. Flaws
Ovarian follicle development and transgenic mouse models
Hum. Reprod. Update, September 1, 2006; 12(5): 537 - 555.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.